Calculated Values
MW: 964.09 Hbond donors: 4 Hbond acceptors: 18 cLogP: 3.14 TPSA: 248.62 SMILES: show CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCN(CC(=O)NCCCOCCOCCOCCCNc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)CC4)cn3)nc2n(C2CCCC2)c1=O Linker type: PEG Incubation time (hours): 4,24 Cells: MiaPaCa2, HPNE Off-targets reported?: No Contributed by: Amit Shraga
Calculated Values
MW: 850.93 Hbond donors: 3 Hbond acceptors: 17 cLogP: 3.16 TPSA: 219.52 SMILES: show CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCN(CCOCCOCCONc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)CC4)cn3)nc2n(C2CCCC2)c1=O Linker type: PEG Incubation time (hours): 4,24 Cells: MiaPaCa2 Off-targets reported?: No Contributed by: Amit Shraga
Calculated Values
MW: 817.91 Hbond donors: 4 Hbond acceptors: 14 cLogP: 3.68 TPSA: 220.93 SMILES: show CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCN(C(=O)NCCCCNc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)CC4)cn3)nc2n(C2CCCC2)c1=O Linker type: Alkane Incubation time (hours): 4,24 Cells: MiaPaCa2 Off-targets reported?: No Contributed by: Amit Shraga
Calculated Values
MW: 816.92 Hbond donors: 3 Hbond acceptors: 14 cLogP: 4.28 TPSA: 208.90 SMILES: show CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCN(CCCCCC(=O)Nc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)CC4)cn3)nc2n(C2CCCC2)c1=O Linker type: Alkane Incubation time (hours): 4,24 Cells: MiaPaCa2 Off-targets reported?: No Contributed by: Amit Shraga
Calculated Values
MW: 874.02 Hbond donors: 4 Hbond acceptors: 14 cLogP: 5.24 TPSA: 220.93 SMILES: show CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCN(C(=O)NCCCCCCCCNc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)CC4)cn3)nc2n(C2CCCC2)c1=O Linker type: Alkane Incubation time (hours): 4,24 Cells: MiaPaCa2 Off-targets reported?: No Contributed by: Amit Shraga |